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MUSE Administration Instructions

Follow directions given by your doctor.

For complete administration instructions, please click here for MUSE Patient Information.

Urinate right before using MUSE.  A moist urethra makes administration of MUSE easier.

Open the foil pouch and remove the MUSE applicator. Twist off the protective cover. Avoid touching the applicator stem and tip

Hold the applicator in a way that is the most comfortable for you.

While sitting or standing (but not lying down), stretch the penis upward to its full length, and slightly squeeze the tip of the penis enough to open the urinary opening.

                 


While keeping the penis stretched, slowly insert the stem of the applicator approximately 1 inch and gently push down the button at the top of the applicator.

Gently rock the applicator from side to side a few times to ensure that the pellet is separated from the stem. Remove the applicator while keeping the penis upright.

While keeping the penis upright, it is important to massage the penis from tip to base or roll the penis between the hands for at least 10 seconds to help ensure that the medication is adequately distributed along the walls of the urethra. If you feel a burning sensation, it may help to continue to massage the penis for an additional 30 to 60 seconds or until the burning subsides.



After massaging the penis, it is important to sit, stand or walk (not lie down) for about 10 minutes while your erection develops. These activities increase blood flow to the penis and will improve the quality of your erection.

Remember, each MUSE is good for a single administration only. Replace the cover on the MUSE applicator, place in the opened foil pouch, fold, and discard as normal household waste.

Important Information:
MUSE (alprostadil) is a medicated pellet that is placed in the urinary opening using a disposable plastic applicator. MUSE should not be used by men who have sickle cell anemia or trait, leukemia or tumor of the bone marrow, allergy to alprostadil (the active ingredient in MUSE), or abnormal penile anatomy. Call your doctor immediately if your erection lasts 4 hours or more.

Men with certain heart problems should not use MUSE. Check with your doctor to see if your heart is healthy enough for sex before using MUSE. You should avoid activities such as driving or other hazardous tasks within one hour of using MUSE because you may become light-headed, dizzy or faint.

Remember that no medicine is for everyone. MUSE should not be used for intercourse with a pregnant woman without a condom. MUSE does not protect against sexually transmitted diseases. Side effects can include penile pain.

 

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